An in vivo comparison of wound healing characteristics of two commercial acellular dermal matrices.

ABSTRACT:

Objectives

Many acellular dermal matrices (ADMs) are available for use in periodontal surgical procedures. However, few studies exist evaluating their in vivo healing properties. The objectives of this study were to compare the wound healing and remodeling of two ADMs used for gingival augmentation procedures in the rat model.

Materials and methods

This was a nonrandomized controlled split-mouth study. Envelope flaps were surgically created in the maxillary quadrants of 24 Sprague Dawley rats. Each received either (a) AlloDerm Regenerative Tissue Matrix, or (b) OrACELL. Gingival tissue from one mandibular quadrant served as the untreated control. Six male and six female rats were treated for 7 or 21 days. Biopsies were processed for histologic analysis (H&E, Picro-sirius red

SUBMITTER: Couto SR 

PROVIDER: S-EPMC8543485 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature