Kidney disease and risk of dementia: a Danish nationwide cohort study.

ABSTRACT:

Objectives

It is unclear whether kidney disease is a risk factor for developing dementia. We examined the association between kidney disease and risk of future dementia.

Design and setting

Nationwide historical registry-based cohort study in Denmark based on data from 1 January 1995 until 31 December 2016.

Participants

All patients diagnosed with kidney disease and matched general population cohort without kidney disease (matched 1:5 on age, sex and year of kidney disease diagnosis).

Primary and secondary outcome measures

All-cause dementia and its subtypes: Alzheimer's disease, vascular dementia and other specified or unspecified dementia. We computed 5-year cumulative incidences (risk) and hazard ratios (HRs) for outcomes using Cox regression analyses.

Res

SUBMITTER: Kjaergaard AD 

PROVIDER: S-EPMC8543681 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature