Radiomics-based machine learning analysis and characterization of breast lesions with multiparametric diffusion-weighted MR.

ABSTRACT:

Background

This study aimed to evaluate the utility of radiomics-based machine learning analysis with multiparametric DWI and to compare the diagnostic performance of radiomics features and mean diffusion metrics in the characterization of breast lesions.

Methods

This retrospective study included 542 lesions from February 2018 to November 2018. One hundred radiomics features were computed from mono-exponential (ME), biexponential (BE), stretched exponential (SE), and diffusion-kurtosis imaging (DKI). Radiomics-based analysis was performed by comparing four classifiers, including random forest (RF), principal component analysis (PCA), L1 regularization (L1R), and support vector machine (SVM). These four classifiers were trained on a training set with 271 patients via ten-fold

SUBMITTER: Sun K 

PROVIDER: S-EPMC8543912 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature