Early pregnancy loss incidence in high-income settings: a protocol for a systematic review and meta-analysis.

ABSTRACT:

Background

Early pregnancy loss (unintended pregnancy loss before 20 completed weeks of gestation) is a common adverse pregnancy outcome, with previous evidence reporting incidence ranging from 10 to 30% of detected pregnancies. The objective of this systematic review and meta-analysis is to determine the incidence and range of early pregnancy loss in contemporary pregnant populations based on studies with good internal and external validity. Findings may be useful for clinical counseling in pre-conception and family planning settings and for people who experience early pregnancy loss.

Methods

We will search MEDLINE, EMBASE, and CINAHL databases using combinations of medical subject headings and keywords. Peer-reviewed, full-text original research articles that meet the foll

SUBMITTER: Schummers L 

PROVIDER: S-EPMC8543941 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature