Ontology highlight
ABSTRACT:
SUBMITTER: Tian Y
PROVIDER: S-EPMC8544304 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Tian Yuan Y Wei Yumei Y Liu Hongmei H Shang Heli H Xu Yuedong Y Wu Tong T Liu Wei W Huang Alan A Dang Qi Q Sun Yuping Y
Aging 20211004 19
Cytotoxic T cells expressing cell surface CD8 played a key role in anti-cancer immunotherapy, including kidney renal clear cell carcinoma (KIRC). Here we set out to comprehensively analyze and evaluate the significance of CD8<sup>+</sup> T cell-related markers for patients with KIRC. We checked immune cell response in KIRC and identified cell type-specific markers and related pathways in the tumor-infiltrating CD8<sup>+</sup> T (TIL-CD8T) cells. We used these markers to explore their prognostic ...[more]