Clinical diversity and treatment results in Tegumentary Leishmaniasis: A European clinical report in 459 patients.

ABSTRACT:

Background

Cutaneous leishmaniasis (CL) is frequent in travellers and can involve oro-nasal mucosae. Clinical presentation impacts therapeutic management.

Methodology

Demographic and clinical data from 459 travellers infected in 47 different countries were collected by members of the European LeishMan consortium. The infecting Leishmania species was identified in 198 patients.

Principal findings

Compared to Old World CL, New World CL was more frequently ulcerative (75% vs 47%), larger (3 vs 2cm), less frequently facial (17% vs 38%) and less frequently associated with mucosal involvement (2.7% vs 5.3%). Patients with mucosal lesions were older (58 vs 30 years) and more frequently immunocompromised (37% vs 3.5%) compared to patients with only skin lesions. Young adults

SUBMITTER: Guery R 

PROVIDER: S-EPMC8544871 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature