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Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021.

ABSTRACT: Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa.

SUBMITTER: Sander AL

PROVIDER: S-EPMC8544961 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Mutations Associated with SARS-CoV-2 Variants of Concern, Benin, Early 2021.

Sander Anna-Lena AL Yadouleton Anges A de Oliveira Filho Edmilson F EF Tchibozo Carine C Hounkanrin Gildas G Badou Yvette Y Adewumi Praise P René Keke K KK Ange Dossou D Sourakatou Salifou S Sedjro Eclou E Aïssi Melchior A J MAJ Fidelia Hinson H Djingarey Mamoudou Harouna MH Nagel Michael M Jo Wendy Karen WK Moreira-Soto Andres A Drosten Christian C Landt Olfert O Corman Victor Max VM Hounkpatin Benjamin B Drexler Jan Felix JF

Emerging infectious diseases 20210831 11

Intense transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Africa might promote emergence of variants. We describe 10 SARS-CoV-2 lineages in Benin during early 2021 that harbored mutations associated with variants of concern. Benin-derived SARS-CoV-2 strains were more efficiently neutralized by antibodies derived from vaccinees than patients, warranting accelerated vaccination in Africa. ...[more]

PMID: 34463240

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