Parallel transmit optimized 3D composite adiabatic spectral-spatial pulse for spectroscopy.

ABSTRACT:

Purpose

To develop a 3D composite adiabatic spectral-spatial pulse for refocusing in spin-echo spectroscopy acquisitions and to compare its performance against standard acquisition methods.

Methods

A 3D composite adiabatic pulse was designed by modulating a train of parallel transmit-optimized 2D subpulses with an adiabatic envelope. The spatial and spectral profiles were simulated and validated by experiments to demonstrate the feasibility of the design in both single and double spin-echo spectroscopy acquisitions. Phantom and in vivo studies were performed to evaluate the pulse performance and compared with semi-LASER with respect to localization performance, sequence timing, signal suppression, and specific absorption rate.

Results

Simultaneous 2D spatial localizat

SUBMITTER: He X 

PROVIDER: S-EPMC8545499 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature