Adaptation to Endophytic Lifestyle Through Genome Reduction by Kitasatospora sp. SUK42.

ABSTRACT: Endophytic actinobacteria offer great potential as a source of novel bioactive compounds. In order to investigate the potential for the production of secondary metabolites by endophytes, we recovered a filamentous microorgansism from the tree Antidesma neurocarpum Miq. After phenotypic analysis and whole genome sequencing we demonstrated that this organism, SUK42 was a member of the actinobacterial genus Kitasatospora. This strain has a small genome in comparison with other type strains of this genus and has lost metabolic pathways associated with Stress Response, Nitrogen Metabolism and Secondary Metabolism. Despite this SUK42 can grow well in a laboratory environment and encodes a core genome that is consistent with other members of the genus. Finally, in contrast to other

SUBMITTER: Zin NM 

PROVIDER: S-EPMC8545861 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature