Non-pharmaceutical interventions and inoculation rate shape SARS-CoV-2 vaccination campaign success

ABSTRACT: Nearly 1 year into the coronavirus disease 2019 pandemic, the first severe acute respiratory syndrome coronavirus 2 vaccines received emergency use authorisation and vaccination campaigns began. A number of factors can reduce the averted burden of cases and deaths due to vaccination. Here, we use a dynamic model, parametrised with Bayesian inference methods, to assess the effects of non-pharmaceutical interventions (NPIs) (such as social distancing, mask mandates, school and workplace closure), and vaccine administration and uptake rates on infections and deaths averted in the United States. We show that scenarios depicting higher compliance with NPIs avert more than 60% of infections and 70% of deaths during the period of vaccine administration, and that increasing the vaccination rate fr

SUBMITTER: Galanti M 

PROVIDER: S-EPMC8545880 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature