Dental Pulp Stem Cells Derived From Adult Human Third Molar Tooth: A Brief Review.

ABSTRACT: The fields of regenerative medicine and stem cell-based tissue engineering have the potential of treating numerous tissue and organ defects. The use of adult stem cells is of particular interest when it comes to dynamic applications in translational medicine. Recently, dental pulp stem cells (DPSCs) have been traced in third molars of adult humans. DPSCs have been isolated and characterized by several groups. DPSCs have promising characteristics including self-renewal capacity, rapid proliferation, colony formation, multi-lineage differentiation, and pluripotent gene expression profile. Nevertheless, genotypic, and phenotypic heterogeneities have been reported for DPSCs subpopulations which may influence their therapeutic potentials. The underlying causes of DPSCs' heterogeneity remain poo

SUBMITTER: Al Madhoun A 

PROVIDER: S-EPMC8545885 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature