Elucidate multidimensionality of type 1 diabetes mellitus heterogeneity by multifaceted information.

ABSTRACT: Type 1 diabetes (T1D) is an autoimmune disease. Different factors, including genetics and viruses may contribute to T1D, but the causes of T1D are not fully known, and there is currently no cure. The advent of high-throughput technologies has revolutionized the field of medicine and biology, and analysis of multi-source data along with clinical information has brought a better understanding of the mechanisms behind disease pathogenesis. The aim of this work was the development of a data repository linking clinical information and interactome studies in T1D. To address this goal, we analyzed the electronic health records and online databases of genes, proteins, miRNAs, and pathways to have a global view of T1D. There were common comorbid diseases such as anemia, hypertension, vitreous disea

SUBMITTER: Chen SJ 

PROVIDER: S-EPMC8545927 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature