The Genome of the CTG(Ser1) Yeast Scheffersomyces stipitis Is Plastic.

ABSTRACT: Microorganisms need to adapt to environmental changes, and genome plasticity can lead to rapid adaptation to hostile environments by increasing genetic diversity. Here, we investigate genome plasticity in the CTG(Ser1) yeast Scheffersomyces stipitis, an organism with an enormous potential for second-generation biofuel production. We demonstrate that S. stipitis has an intrinsically plastic genome and that different S. stipitis isolates have genomes with distinct chromosome organizations. Real-time evolution experiments show that S. stipitis genome plasticity is common and rapid since extensive genomic changes with fitness benefits are detected following in vitro evolution experiments. Hybrid MinION Nanopore and Illumina genome sequencing identify retrotra

SUBMITTER: Vega-Estevez S 

PROVIDER: S-EPMC8546629 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature