Obesity as an isolated contraindication to kidney transplantation in the end-stage renal disease population: A cohort study.

ABSTRACT:

Objective

The aim of this study was to characterize end-stage renal disease (ESRD) patients with obesity as their only contraindication to listing and to quantify wait-list and transplant access.

Methods

Using the US Renal Data System, a retrospective cohort study of incident dialysis cases (2012 to 2014) was performed. The primary outcomes were time to wait-listing and time to transplantation.

Results

Of 157,572 dialysis patients not already listed, 39,844 had BMI as their only demonstrable transplant contraindication. They tended to be younger, female, and Black. Compared with patients with BMI < 35, those with BMI 35 to 39.9, 40 to 44.9, and ≥45 were, respectively, 15% (adjusted hazard ratio [aHR] 0.85; 95% CI: 0.83-0.88; p < 0.001), 45% (aHR 0.55; 95% CI: 0.52-0.5

SUBMITTER: Orandi BJ 

PROVIDER: S-EPMC8547159 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature