Differential systemic inflammatory responses after TAVI: The role of self versus balloon expandable devices.

ABSTRACT:

Objective

Transcatheter aortic valve implantation (TAVI) provokes early injury response, represented in part by dynamic changes in the inflammatory markers. The association of self-expanding valves (SEVs) and balloon-expandable valves (BEVs) with the consequent inflammatory response remains uncertain.

Materials and methods

Patients with severe symptomatic aortic stenosis who underwent transfemoral TAVI: SEVs or BEVs, from January 2010 to December 2019 were enrolled. Whole white blood cells (WBC) and subpopulation dynamics as well the neutrophil to lymphocyte ratio (NLR) were evaluated.

Results

Three-hundred seventy consecutive patients (mean age 81.75 ± 6.8 years, 199 women's) were enrolled. In the entire population, significant kinetic changes in the WBC response (p

SUBMITTER: Abu Khadija H 

PROVIDER: S-EPMC8547641 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature