A haploscope based binocular pupillometer system to quantify the dynamics of direct and consensual Pupillary Light Reflex.

ABSTRACT: This study described the development of a haploscope-based pupillometer for the parametrization of the Pupillary Light Reflex (PLR), and its feasibility in a set of 30 healthy subjects (light or dark-colored irides) and five patients diagnosed with Relative Afferent Pupillary Defect (RAPD). Our supplementary aim focused on evaluating the influence of iris colour on the PLR to decide whether a difference in PLR parameters should be anticipated when this system is used across ethnicities. All the participants underwent a customized pupillometry protocol and the generated pupil traces, captured by an eye tracker, were analyzed using exponential fits to derive PLR parameters. A Pupil Response Symmetry (PRS) coefficient was calculated to predict the presence of RAPD. The mean (SD) Initial PD du

SUBMITTER: Meethal NSK 

PROVIDER: S-EPMC8548319 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature