Brain connectivity dynamics in cisgender and transmen people with gender incongruence before gender affirmative hormone treatment.

ABSTRACT: Large-scale brain network interactions have been described between trans- and cis-gender binary identities. However, a temporal perspective of the brain's spontaneous fluctuations is missing. We investigated the functional connectivity dynamics in transmen with gender incongruence and its relationship with interoceptive awareness. We describe four states in native and meta-state spaces: (i) one state highly prevalent with sparse overall connections; (ii) a second with strong couplings mainly involving components of the salience, default, and executive control networks. Two states with global sparse connectivity but positive couplings (iii) within the sensorimotor network, and (iv) between salience network regions. Transmen had more dynamical fluidity than cismen, while cismen presented les

SUBMITTER: Uribe C 

PROVIDER: S-EPMC8548343 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature