Systematic review with meta-analysis of diagnostic test accuracy for COVID-19 by mass spectrometry.

ABSTRACT:

Background

The global COVID-19 pandemic has led to extensive development in many fields, including the diagnosis of COVID-19 infection by mass spectrometry. The aim of this systematic review and meta-analysis was to assess the accuracy of mass spectrometry diagnostic tests developed so far, across a wide range of biological matrices, and additionally to assess risks of bias and applicability in studies published to date.

Method

23 retrospective observational cohort studies were included in the systematic review using the PRISMA-DTA framework, with a total of 2858 COVID-19 positive participants and 2544 controls. Risks of bias and applicability were assessed via a QUADAS-2 questionnaire. A meta-analysis was also performed focusing on sensitivity, specificity, diagnostic accur

SUBMITTER: Spick M 

PROVIDER: S-EPMC8548837 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature