Age moderates the relationships between obesity, glucose variability, and intensive care unit mortality: a retrospective cohort study.

ABSTRACT:

Background

Although the associations between obesity, glucose variability (GV), and Intensive Care Unit (ICU) mortality have been studied extensively, whether age moderates these associations is not well understood.

Materials and methods

The medical records of 1062 patients, who were admitted into ICU at Sir Run Run Shaw Hospital (Zhejiang, China), were studied. Logistic regression was used to test the associations between obesity, GV, and ICU mortality. Furthermore, the moderation effect of age was tested.

Results

After controlling for covariates, the underweight group had the highest odds of death (OR 2.38, 95% CI 1.43-3.95, p < 0.001) in comparison with the control group (overweight). However, normal weight (OR 1.29, 95% CI 0.88-1.89, p = 0.185) and obese (OR 1.08,

SUBMITTER: Lu L 

PROVIDER: S-EPMC8549309 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature