Geographical separation and ethnic origin influence the human gut microbial composition: a meta-analysis from a Malaysian perspective.

ABSTRACT: Ethnicity is consistently reported as a strong determinant of human gut microbiota. However, the bulk of these studies are from Western countries, where microbiota variations are mainly driven by relatively recent migration events. Malaysia is a multicultural society, but differences in gut microbiota persist across ethnicities. We hypothesized that migrant ethnic groups continue to share fundamental gut traits with the population in the country of origin due to shared cultural practices despite subsequent geographical separation. To test this hypothesis, the 16S rRNA gene amplicons from 16 studies comprising three major ethnic groups in Malaysia were analysed, covering 636 Chinese, 248 Indian and 123 Malay individuals from four countries (China, India, Indonesia and Malaysia). A confounde

SUBMITTER: Dwiyanto J 

PROVIDER: S-EPMC8549367 | biostudies-literature | 2021 Aug

REPOSITORIES: biostudies-literature