A molecular epidemiological study of pediatric norovirus gastroenteritis, 2017-2019.

ABSTRACT:

Objectives

To study the molecular epidemiological characteristics of norovirus in children with acute gastroenteritis from 2017 to 2019.

Methods

A retrospective analysis was performed on the medical data of children with acute gastroenteritis who were admitted to Children's Hospital of Chongqing Medical University from January 2017 to December 2019. A total of 1 458 stool samples were collected from the children, and viral RNA was extracted. Reverse transcription polymerase chain reaction was used for gene amplification, sequencing, and genotype identification of the VP1 region of capsid protein in norovirus.

Results

Among the 1 458 stool samples, 158 (10.8%) were positive for norovirus. There was no significant difference in the positive detection rate of norovirus b

SUBMITTER: Duan ML 

PROVIDER: S-EPMC8549646 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature