Three-Day Dietary Manipulation in Multiple Sclerosis: Exercise and Fatigue Outcomes.

ABSTRACT:

Background

In persons with multiple sclerosis (MS), the effect of nutrition on exercise performance and fatigue remains unknown. The objective was to determine whether a 3-day diet high in triglycerides (FAT) compared with a 3-day diet high in carbohydrates (CARB) would improve fatigue and exercise performance in persons with MS.

Methods

A randomized controlled crossover design was incorporated to study FAT versus CARB on submaximal cycling endurance (60% of peak oxygen consumption), substrate utilization, and fatigue in 12 persons with mild-to-moderate MS (Expanded Disability Status Scale score, 2.0-5.0) and 12 age- and sex-matched controls.

Results

There were no differences in cycling time between diets in either group (P = .29). The MS group had no changes i

SUBMITTER: Bromley LE 

PROVIDER: S-EPMC8550483 | biostudies-literature | 2021 Sep-Oct

REPOSITORIES: biostudies-literature