CAR T cell therapy in solid tumors: a short review.
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ABSTRACT:
SUBMITTER: Umut O
PROVIDER: S-EPMC8550638 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Publications
CAR T cell therapy in solid tumors: a short review.
Umut Öykü Ö Gottschlich Adrian A Endres Stefan S Kobold Sebastian S
Memo 20210408 2
Chimeric antigen receptor (CAR) T cell therapy has been established in the treatment of hematological malignancies. However, in solid tumors its efficacy remains limited. The aim of this article is to give an overview of the field of cell therapy itself, to introduce the underlying concepts of CAR T cell-based treatment approaches and to address its limitations in advancing the treatment for solid malignancies. ...[more]
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