Diabetes mellitus as a risk factor for chemotherapy-induced peripheral neuropathy: a meta-analysis.

ABSTRACT:

Background

To identify the association between diabetes mellitus (DM) and the risk of chemotherapy-induced peripheral neuropathy (CIPN) through a systematic review and meta-analysis.

Methods

An electronic literature search was conducted in PubMed, Embase, Web of Science, the Wanfang database, the VIP Journals database (CQVIP), the China National Knowledge Infrastructure (CNKI) database, and the China Biology Medicine database (Sinomed) between January 2010 and January 2021. Articles were included if they investigated CIPN and DM. Stata 15.1 was used to analyze the data.

Results

We examined 8923 cancer patients from 25 studies comprising 9 cohort studies and 16 case-control studies. Meta-analysis showed that there was a statistically significant positive correlation be

SUBMITTER: Gu J 

PROVIDER: S-EPMC8550712 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature