Molecular epidemiology and multidrug resistance of Mycobacterium tuberculosis complex from pulmonary tuberculosis patients in the Eastern region of Ghana.

ABSTRACT:

Background

Tuberculosis (TB) and drug-resistant TB (DR-TB) continue to persist as a serious public health challenges in Ghana. Although several research has evaluated the drug resistance of Mycobacterium tuberculosis complex (MTBc) strains across the country, there is a paucity of data on its magnitude as well as the various lineages circulating in the Eastern region of Ghana.

Objective

This study therefore evaluated the distribution of the various lineages of MTBc in the Eastern region of the country and the associated drug resistance.

Materials and methods

One hundred and forty-three (143) patients with pulmonary TB attending the Eastern Regional Hospital, Koforidua/Ghana were included in the study. The BACTEC MGIT 960 tube media was used for both sput

SUBMITTER: Thumamo Pokam BD 

PROVIDER: S-EPMC8551511 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature