Drug susceptibility and molecular epidemiology of Escherichia coli in bloodstream infections in Shanxi, China.

ABSTRACT:

Objectives

We carried out a retrospective study to investigate the drug susceptibility and genetic relationship of clinical Escherichia coli isolates from patients with BSIs in Shanxi, China.

Methods

E. coli isolates causing BSIs were consecutively collected from June 2019 to March 2020. Antimicrobial susceptibility testing was performed by broth microdilution method. PCR was used to detect antimicrobial resistance genes coding for extended-spectrum β-lactamases (ESBLs), phylogenetic groups and seven housekeeping genes of E. coli.

Results

A total of 76 E. coli were collected. Antimicrobial susceptibility testing revealed that the top six E. coli resistant antibiotics were ampicillin (90.7%), ciprofloxacin (69.7%), cefazolin (65.7%),

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8552779 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature