The MpsAB Bicarbonate Transporter Is Superior to Carbonic Anhydrase in Biofilm-Forming Bacteria with Limited CO₂ Diffusion.

ABSTRACT: CO₂ and bicarbonate are required for carboxylation reactions, which are essential in most bacteria. To provide the cells with sufficient CO₂, there exist two dissolved inorganic carbon supply (DICS) systems: the membrane potential-generating system (MpsAB) and the carbonic anhydrase (CA). Recently, it has been shown that MpsAB is a bicarbonate transporter that is present not only in photo- and autotrophic bacteria, but also in a diverse range of nonautotrophic microorganisms. Since the two systems rarely coexist in a species but are interchangeable, we investigated what advantages the one system might have over the other. Using the genus Staphylococcus as a model, we deleted the CA gene can in Staphylococcus carnosus and mpsABC genes in Staphylococcus au

SUBMITTER: Fan SH 

PROVIDER: S-EPMC8552792 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature