High risk of acute kidney injury in Malawian trauma patients: a prospective observational cohort study.

ABSTRACT:

Background

Trauma is a common cause of acute kidney injury (AKI). Yet little data exist regarding trauma-related-AKI in low-resourced settings, where the majority of deaths from AKI and trauma occur. We prospectively evaluated epidemiology of AKI in hospitalized Malawian trauma patients.

Methods

AKI was defined by creatinine-only Kidney Disease Improving Global Outcomes (KDIGO) criteria. Those with AKI were followed up 3-6 months later to determine persistent kidney abnormalities. We calculated univariate statistics with Wilcoxon rank sum tests, Fisher's exact, and chi-square tests to compare those with and without AKI. Multivariate log-risk regression modelling was used to determine risk ratios (RR) and 95% confidence intervals (CI) for AKI development.

Results

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SUBMITTER: Bjornstad EC 

PROVIDER: S-EPMC8552973 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature