AQP4-IgG positive paraneoplastic NMOSD: A case report and review.

ABSTRACT:

Introduction

Neuromyelitis optica spectrum disorder (NMOSD; also known as Devic syndrome) is a clinical syndrome of central nervous system characterized by immune mediated attacks of acute optic neuritis and myelitis. Paraneoplastic neurological syndrome is a group of nervous system disorders resulting from the remote immune effects of malignant neoplasm. NMOSD occurs mostly in young people, and tumor is not a common cause, especially recurrent tumor.

Methods

We reported a case of a 59-year-old man who developed anti-aquaporin-4 IgG positive longitudinally extensive myelitis. We also summarized and analyzed previously reported cases of paraneoplastic NMOSD.

Results

Among these 43 patients, 88.4% patients are female. The largest number of patients is between 60 and 69

SUBMITTER: Ding M 

PROVIDER: S-EPMC8553315 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature