Challenging the gold standard: methods of sampling for microbial culture in patients with chronic rhinosinusitis.

ABSTRACT:

Purpose

Chronic rhinosinusitis (CRS) is a highly prevalent multifactorial disorder. Culture-directed antibiotics are frequently prescribed to patients with CRS and the middle nasal meatus (MM) is traditionally believed to be a representative sampling site of the sinuses as a whole. The purpose of our study was to reevaluate the reliability of the MM as a sampling site in patients with CRS who suffer from impaired drainage from the sinuses to the MM.

Methods

Swabs and tissue biopsies were collected from the MM, maxillary sinus and frontal sinus from 50 patients with CRS. The results of bacterial culture were compared between sampling methods and sites in relation to the patency of the sinus ostia.

Results

782 bacterial isolates were cultured from the samples. Concordan

SUBMITTER: Szaleniec J 

PROVIDER: S-EPMC8553703 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature