Gene Therapy in Inherited Retinal Diseases: An Update on Current State of the Art.

ABSTRACT: Background: Gene therapy cannot be yet considered a far perspective, but a tangible therapeutic option in the field of retinal diseases. Although still confined in experimental settings, the preliminary results are promising and provide an overall scenario suggesting that we are not so far from the application of gene therapy in clinical settings. The main aim of this review is to provide a complete and updated overview of the current state of the art and of the future perspectives of gene therapy applied on retinal diseases. Methods: We carefully revised the entire literature to report all the relevant findings related to the experimental procedures and the future scenarios of gene therapy applied in retinal diseases. A clinical background and a detailed description of the g

SUBMITTER: Amato A 

PROVIDER: S-EPMC8553993 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature