Examining the bidirectional association between emotion recognition and social autistic traits using observational and genetic analyses.

ABSTRACT:

Background

There is mixed evidence for an association between autism spectrum disorder (ASD) and emotion recognition deficits. We sought to assess the bidirectionality of this association using phenotypic and genetic data in a large community sample.

Methods

Analyses were conducted in three stages. First, we examined the bidirectional association between social autistic traits at age 8 years and emotion recognition task (ERT) responses at age 24 years (Study 1; N = 3,562); and between Diagnostic Analysis of Non-Verbal Accuracy (DANVA) emotion recognition responses at age 8 years and social autistic traits at age 10 years (Study 2; N = 9,071). Next, we used genetic analyses (Study 3) to examine the association between polygenic risk scores for ASD and outcomes for the ERT and

SUBMITTER: Reed ZE 

PROVIDER: S-EPMC8554526 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature