A Microbial Electrochemical Technology to Detect and Degrade Organophosphate Pesticides.

ABSTRACT: Organophosphate (OP) pesticides cause hundreds of illnesses and deaths annually. Unfortunately, exposures are often detected by monitoring degradation products in blood and urine, with few effective methods for detection and remediation at the point of dispersal. We have developed an innovative strategy to remediate these compounds: an engineered microbial technology for the targeted detection and destruction of OP pesticides. This system is based upon microbial electrochemistry using two engineered strains. The strains are combined such that the first microbe (E. coli) degrades the pesticide, while the second (S. oneidensis) generates current in response to the degradation product without requiring external electrochemical stimulus or labels. This cellular technology is uniq

SUBMITTER: Karbelkar AA 

PROVIDER: S-EPMC8554842 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature