Association between depression and antibiotic use: analysis of population-based National Health Insurance claims data.

ABSTRACT:

Background

Frequent exposure to antibiotic treatments may increase the risk of antibiotic resistance, which may threaten the effectiveness of future antibiotic treatments. Thus, it is important to identify the preventable risks in terms of antibiotic use. This study assessed the association between major depressive disorder (MDD) and antibiotic use by comparing the likelihood and extent of antibiotic use between patients with and without MDD.

Methods

This retrospective cross-sectional study utilized the National Patients Sample data from the 2017 Health Insurance Review and Assessment Service. We analyzed 16,950 patients with MDD, defined as those with at least two claims records stating a primary diagnosis of MDD (International Classification of Diseases, 10th revision code

SUBMITTER: Lee JW 

PROVIDER: S-EPMC8554858 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature