High regional mortality due to malignant melanoma in Eastern Finland may be explained by the increase in aggressive melanoma types.

ABSTRACT:

Background

A regional skin cancer prevention program in Eastern Finland revealed a relatively high age-standardized mortality due to malignant melanoma during 2013-2017. An explanation for this is needed.

Purpose

To analyse the 543 melanoma samples in 524 subjects collected during 2000-2013 at Kuopio University Hospital and reposited in the Biobank of Eastern Finland. A focus was directed to factors related to metastasis.

Methods

The samples were analysed anonymously by examining the histopathological report, referral text and the list of diagnoses. A possible state of immunosuppression was evaluated.

Results

The mean age at the diagnosis of malignant melanoma (MM), lentigo maligna (LM) and melanoma in situ was relatively high, i.e., 66.2, 72.1 and 63.3, respec

SUBMITTER: Suhonen V 

PROVIDER: S-EPMC8555296 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature