Transmission of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) from pre and asymptomatic infected individuals: a systematic review.

ABSTRACT:

Background

The role of SARS-Cov-2-infected persons who develop symptoms after testing (presymptomatics) or not at all (asymptomatics) in the pandemic spread is unknown.

Objectives

To determine infectiousness and probable contribution of asymptomatic persons (at the time of testing) to pandemic SARS-CoV-2 spread.

Data sources

LitCovid, medRxiv, Google Scholar, and WHO Covid-19 databases (to 31 March 2021) and references in included studies.

Study eligibility criteria

Studies with a proven or hypothesized transmission chain based either on serial PCR cycle threshold readings and/or viral culture and/or gene sequencing, with adequate follow-up.

Participants

People exposed to SARS-CoV-2 within 2-14 days to index asymptomatic (at time of observation) infected

SUBMITTER: Jefferson T 

PROVIDER: S-EPMC8555342 | biostudies-literature | 2022 Feb

REPOSITORIES: biostudies-literature