Dataset Information

Long term dual antiretroviral therapy: A real life retrospective countrywide Israeli study.

ABSTRACT:

Aim

Combined antiretroviral treatment (cART) traditionally consists of three antiretroviral medications, while two-drug regimens (2DR), historically used infrequently, recently been suggested to be non-inferior to three-drug regimens, is emerging as a potential treatment option and is currently a recommended option for treatment initiation in many guidelines.

Purpose

Characterize the indications and clinical efficacy of 2DR use at a real-life setting in a nation-wide survey.

Methods

A cross-sectional survey of Israeli patients treated by 2DR until July 2019, included demographic, immunologic, virologic, genotypic and biochemical/metabolic parameters at diagnosis, ART initiation, 2DR initiation and following 24, 48, 96 and 144 weeks of 2DR treatment.