Ontology highlight
ABSTRACT:
SUBMITTER: Feng ZH
PROVIDER: S-EPMC8556261 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Feng Zhen-Hua ZH Zheng Lin L Yao Teng T Tao Si-Yue SY Wei Xiao-An XA Zheng Ze-Yu ZY Zheng Bing-Jie BJ Zhang Xu-Yang XY Huang Bao B Liu Jun-Hui JH Chen Yi-Lei YL Shan Zhi Z Yuan Pu-Tao PT Wang Cheng-Gui CG Chen Jian J Shen Shu-Ying SY Zhao Feng-Dong FD
Cell death & disease 20211029 11
Emerging evidence indicates that circRNAs are broadly expressed in osteosarcoma (OS) cells and play a crucial role in OS progression. Recently, cancer-specific circRNA circPRKAR1B has been identified by high-throughput sequencing and is recorded in publicly available databases. Nevertheless, the detailed functions and underlying mechanisms of circPRKAR1B in OS remains poorly understood. By functional experiments, we found that circPRKAR1B enhanced OS cell proliferation, migration, and promotes O ...[more]