Early Vocal Development in Tuberous Sclerosis Complex.

ABSTRACT:

Background

Our goal was to assess for the first time early vocalizations as precursors to speech in audio-video recordings of infants with tuberous sclerosis complex (TSC).

Methods

We randomly selected 40 infants with TSC from the TSC Autism Center of Excellence Research Network dataset. Using human observers, we analyzed 74 audio-video recordings within a flexible software-based coding environment. During the recordings, infants were engaged in developmental testing. We determined syllables per minute (volubility), the number of consonant-vowel combinations, such as 'ba' (canonical babbling), and the canonical babbling ratio (canonical syllables/total syllables) and compared the data with two groups of typically developing (TD) infants. One comparison group's data had come

SUBMITTER: Gipson TT 

PROVIDER: S-EPMC8557126 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature