Carbon nanodot-based electrogenerated chemiluminescence biosensor for miRNA-21 detection.

ABSTRACT: A simple carbon nanodot-based electrogenerated chemiluminescence biosensor is described for sensitive and selective detection of microRNA-21 (miRNA-21), a biomarker of several pathologies including cardiovascular diseases (CVDs). The photoluminescent carbon nanodots (CNDs) were obtained using a new synthesis method, simply by treating tiger nut milk in a microwave reactor. The synthesis is environmentally friendly, simple, and efficient. The optical properties and morphological characteristics of the CNDs were exhaustively investigated, confirming that they have oxygen and nitrogen functional groups on their surfaces and exhibit excitation-dependent fluorescence emission, as well as photostability. They act as co-reactant agents in the anodic electrochemiluminescence (ECL) of [Ru(bpy)

SUBMITTER: Gutierrez-Galvez L 

PROVIDER: S-EPMC8557186 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature