Diabetes, hypertension, body mass index, smoking and COVID-19-related mortality: a systematic review and meta-analysis of observational studies.

ABSTRACT:

Objectives

We conducted a systematic literature review and meta-analysis of observational studies to investigate the association between diabetes, hypertension, body mass index (BMI) or smoking with the risk of death in patients with COVID-19 and to estimate the proportion of deaths attributable to these conditions.

Methods

Relevant observational studies were identified by searches in the PubMed, Cochrane library and Embase databases through 14 November 2020. Random-effects models were used to estimate summary relative risks (SRRs) and 95% CIs. Certainty of evidence was assessed using the Cochrane methods and the Grading of Recommendations, Assessment, Development and Evaluations framework.

Results

A total of 186 studies representing 210 447 deaths among 1 304 587 pat

SUBMITTER: Mahamat-Saleh Y 

PROVIDER: S-EPMC8557249 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature