Detection of mRNA Expression and Copy Number Variations Within the Goat Fec ^B Gene Associated With Litter Size.

ABSTRACT: The Booroola fecundity (Fec ^B ) gene, as the first major fecundity gene identified in Booroola sheep, has attracted careful attention. So far, previous research have uncovered the Fec^B mutation (Q249R) as the main mutation by virtue of which sheep exhibits multiple lambing phenomena. This mutation is now being intensively studied and widely used. However, such effect of the Fec^B mutation has not been applied to goats, and similar types of the Fec ^B gene in goats still need to be studied. Thus, the current study attempted to verify potential mutations in the goat Fec ^B gene as well as investigate their functions related to fecundity. First, Fec ^B expression was investiga

SUBMITTER: Bi Y 

PROVIDER: S-EPMC8558618 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature