The Influence of Transcranial Magnetoacoustic Stimulation Parameters on the Basal Ganglia-Thalamus Neural Network in Parkinson's Disease.

ABSTRACT: Objective: Parkinson's disease (PD) is a degenerative disease of the nervous system that frequently occurs in the aged. Transcranial magnetoacoustic stimulation (TMAS) is a neuronal adjustment method that combines sound fields and magnetic fields. It has the characteristics of high spatial resolution and noninvasive deep brain focusing. Methods: This paper constructed a simulation model of TMAS based on volunteer's skull computer tomography, phased controlled transducer and permanent magnet. It simulates a transcranial focused sound pressure field with the Westervelt equation and builds a basal ganglia and thalamus neural network model in the PD state based on the Hodgkin-Huxley model. Results: A biased sinusoidal pulsed ultrasonic TMAS induced current with 0.3 T stati

SUBMITTER: Zhang Y 

PROVIDER: S-EPMC8558679 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature