Obese patients with higher TSH levels had an obvious metabolic improvement after bariatric surgery.

ABSTRACT:

Objective

Bariatric surgery has become the most effective treatment for morbid obesity. Increasing evidence showed that bariatric surgery can alleviate insulin resistance and influence thyroid function. This study aimed to investigate the relationship between changes in thyroid function and adipose tissue insulin resistance (adipo-IR) after bariatric surgery.

Methods

A total of 287 non-diabetic participants with regular thyroid function were recruited and divided into the lean, overweight and obese groups. Among them, 50 morbidly obese patients submitted to bariatric surgery.

Results

The obese group had a higher level of adipo-IR, thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), FT3/free thyroxine (FT4) and metabolism disorders than the lean and overwei

SUBMITTER: Bian N 

PROVIDER: S-EPMC8558898 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature