Dynamic survival analysis of gastrointestinal stromal tumors (GISTs): a 10-year follow-up based on conditional survival.

ABSTRACT:

Background

The prognosis of patients with gastrointestinal stromal tumors (GISTs) is generally evaluated at the time of diagnosis but does not reflect the survival dynamics of patients in the future. Therefore, the purpose of this article was to evaluate the conditional survival (CS) of Chinese patients with GISTs after radical resection.

Methods

This retrospective study included 451 patients who underwent radical surgery for GISTs. A Cox proportional hazard model was used to evaluate the prognostic factors of disease-free survival (DFS). The 3-year conditional DFS (CDFS₃) of patients who survived for x years was expressed as CDFS₃₌DFS_(x + 3)/DFS_(x).

Results

The traditional 3-year DFS rate decreased gradually from 94.0% at 3

SUBMITTER: Xu SJ 

PROVIDER: S-EPMC8559392 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature