Overall survival after recurrence in stage I-III colorectal cancer patients in accordance with the recurrence organ site and pattern.

ABSTRACT:

Aim

This study aimed to investigate the prognosis after recurrence in patients with stage I-III colon cancer (CC) and rectal cancer (RC).

Methods

Cancer recurred in 116 (15.2%) out of 763 patients with stage I-III colorectal cancer. The overall survival (OS) after recurrence was evaluated based on the recurrence organs and patterns.

Results

The first recurrence occurred in the lungs, livers, lymph nodes, and other sites in 32, 22, 12, and 2 patients, respectively. It was localized, disseminated, and involved two or more organs in 14, 9, and 25 patients, respectively. Patients with CC had a shorter OS after recurrence as compared to those with RC (P = .0103). Compared to other organ metastasis, liver metastasis was associated with an earlier recurrence (P

SUBMITTER: Sawayama H 

PROVIDER: S-EPMC8560596 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature