Poly(N,N-dimethylacrylamide)-coated upconverting NaYF₄:Yb,Er@NaYF₄:Nd core-shell nanoparticles for fluorescent labeling of carcinoma cells.

ABSTRACT: Upconverting luminescent lanthanide-doped nanoparticles (UCNP) belong to promising new materials that absorb infrared light able to penetrate in the deep tissue level, while emitting photons in the visible or ultraviolet region, which makes them favorable for bioimaging and cell labeling. Here, we have prepared upconverting NaYF₄:Yb,Er@NaYF₄:Nd core-shell nanoparticles, which were coated with copolymers of N,N-dimethylacrylamide (DMA) and 2-(acryloylamino)-2-methylpropane-1-sulfonic acid (AMPS) or tert-butyl [2-(acryloylamino)ethyl]carbamate (AEC-Boc) with negative or positive charges, respectively. The copolymers were synthesized by a reversible addition-fragmentation chain transfer (RAFT) polymerization, reaching M_n ~ 11 kDa and containing ~ 5 mol% of rea

SUBMITTER: Oleksa V 

PROVIDER: S-EPMC8560758 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature