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Long-term priors influence visual perception through recruitment of long-range feedback.

ABSTRACT: Perception results from the interplay of sensory input and prior knowledge. Despite behavioral evidence that long-term priors powerfully shape perception, the neural mechanisms underlying these interactions remain poorly understood. We obtained direct cortical recordings in neurosurgical patients as they viewed ambiguous images that elicit constant perceptual switching. We observe top-down influences from the temporal to occipital cortex, during the preferred percept that is congruent with the long-term prior. By contrast, stronger feedforward drive is observed during the non-preferred percept, consistent with a prediction error signal. A computational model based on hierarchical predictive coding and attractor networks reproduces all key experimental findings. These results suggest a pattern of large-scale information flow change underlying long-term priors' influence on perception and provide constraints on theories about long-term priors' influence on perception.

SUBMITTER: Hardstone R

PROVIDER: S-EPMC8560909 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature

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Long-term priors influence visual perception through recruitment of long-range feedback.

Hardstone Richard R Zhu Michael M Flinker Adeen A Melloni Lucia L Devore Sasha S Friedman Daniel D Dugan Patricia P Doyle Werner K WK Devinsky Orrin O He Biyu J BJ

Nature communications 20211101 1

Perception results from the interplay of sensory input and prior knowledge. Despite behavioral evidence that long-term priors powerfully shape perception, the neural mechanisms underlying these interactions remain poorly understood. We obtained direct cortical recordings in neurosurgical patients as they viewed ambiguous images that elicit constant perceptual switching. We observe top-down influences from the temporal to occipital cortex, during the preferred percept that is congruent with the l ...[more]

PMID: 34725348

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Long-term priors influence visual perception through recruitment of long-range feedback.

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Long-term priors influence visual perception through recruitment of long-range feedback.

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