An isotropic EPI database and analytical pipelines for rat brain resting-state fMRI.

ABSTRACT: Resting-state functional magnetic resonance imaging (fMRI) has drastically expanded the scope of brain research by advancing our knowledge about the topologies, dynamics, and interspecies translatability of functional brain networks. Several databases have been developed and shared in accordance with recent key initiatives in the rodent fMRI community to enhance the transparency, reproducibility, and interpretability of data acquired at various sites. Despite these pioneering efforts, one notable challenge preventing efficient standardization in the field is the customary choice of anisotropic echo planar imaging (EPI) schemes with limited spatial coverage. Imaging with anisotropic resolution and/or reduced brain coverage has significant shortcomings including reduced registration accuracy

SUBMITTER: Lee SH 

PROVIDER: S-EPMC8561231 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature