Transcriptomic analysis of the Myxococcus xanthus FruA regulon, and comparative developmental transcriptomic analysis of two fruiting body forming species, Myxococcus xanthus and Myxococcus stipitatus.

ABSTRACT:

Background

The Myxococcales are well known for their predatory and developmental social processes, and for the molecular complexity of regulation of these processes. Many species within this order have unusually large genomes compared to other bacteria, and their genomes have many genes that are unique to one specific sequenced species or strain. Here, we describe RNAseq based transcriptome analysis of the FruA regulon of Myxococcus xanthus and a comparative RNAseq analysis of two Myxococcus species, M. xanthus and Myxococcus stipitatus, as they respond to starvation and begin forming fruiting bodies.

Results

We show that both species have large numbers of genes that are developmentally regulated, with over half the genome showing statistically significant changes in express

SUBMITTER: McLoon AL 

PROVIDER: S-EPMC8561891 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature